We recently reported on a discipline that says serious runners marking their miles lean to think about howrunning kind of suction . But how do you square that negativity with the well - known , wide reported euphoria known as runner ’s high ?
A novel sketch in the journalCell Metabolismsuggests that high is the result of a decrement in the hormone leptin , which is associated with feel sated . As your levels of leptin dwindle , they send a hungriness signaling to your brain , which secrete Intropin to increase your stamen and keep you running in the pursuit of food .
In the subject field , mouse were genetically altered to step in with their brains ’ leptin sign pathway , disrupting the expiration of dopamine in reaction to leptin . These mouse ladder twice as many nautical mile on their wheels as normal mouse . The decrease in leptin signaling seemed to increase the dopamine - link up reward assort with track , inducing positive feelings about the task at hired hand — an vantage if your physical structure recall you ’re thirsty and call for nutrients .
" free-base on these findings , we guess that a autumn in leptin levels increases motivation for physical activity as a means to enhance exploration and the sideline of food , " study atomic number 27 - author Stephanie Fulton , a research worker at the University of Montreal , says in apress statement . “ Our survey also propose that people with lower fat - adjust leptin levels , such as high - performance marathon runners , could potentially be more susceptible to the rewarding effects of running and thus maybe more inclined to exercise , ” she explain .
Leptin probably is n’t the only hormone involved in runner ’s high , but it does seem to play a vital role . Previous inquiry has also associate low leptin levels with the desire to move , finding associations with low leptin levels andexercise addictionas well as hyperactivity inanorexic patients .
[ h / t : Washington Post ]
