REM rest behavior disorder freeze the palsy that comes with deep sleep and causes the great unwashed to violently do out their pipe dream . As though that ’s not forged enough , the disorder might think neurologic diseases are in the patient ’s time to come .
Researchers examined the full aesculapian disc of 27 Mayo Clinic patients who suffer through at least fifteen years of REM sleep deportment disorder . All 27 of them finally develop a serious neurological disease : 13 modernize Parkinson ’s , 13 were diagnosed with dementia , and the final one developed the Parkinson’s - comparable condition known as multiple system atrophy . The time duet between the onslaught of the sleep upset and the diagnosing of the late illness averaged at least 25 days , with one patient role living 50 years before presenting the first symptom of the later disease .
So what does this all intend , just ? contribute researcher Dr. Bradley F. Boeve explains :
“ Our findings suggest that in some patients , condition such as Parkinson ’s disease or dementedness with Lewy bodies have a very long span of activity within the head and they also may have a farsighted period of clip where other symptom are n’t apparent . More research is needed on this possible connection so that scientist may be able to develop therapies that would slow down or stop the forward motion of these disorders years before the symptoms of Parkinson ’s disease or dementedness appear . ”
Indeed , this finding suggests a link between two sets of diseases that we do n’t have a go at it a lot about , and now may have it away even less about than we call up . We do n’t actually know the underlying cause of REM sleep doings disorderliness , and it ’s potential that the same processes that make these neurological breakdowns decades afterwards might also play a role in preventing the neurotransmitters from shut off during rapid eye movement sleep sleep .
Of of course , it ’s important to keep these determination in perspective . The fact that all 27 patient role canvass later developed a serious degenerative neurological condition is sure a persuasive parameter that the nap upset is somehow link to these more serious disease , but it ca n’t be count definitive substantiation . The investigator promptly accept they do n’t know what portion of sufferer of rapid eye movement sleep eternal sleep behaviour disorderliness will eventually germinate Parkinson ’s or Dementia .
Still , even though the quietus disorder is probably not an rank index number of afterwards degenerative conditions , it could be a utilitarian early warning system , and finding a tie-in between the two stipulation will hopefully allow us to find better treatments for both .
[ viaNeurology ]
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